Weight Loss Medications

Every FDA-approved weight loss medication in one place, medically reviewed and written to be understood by patients.

6 FDA Approved
Updated
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๐Ÿ’Š FDA-Approved Pills Oral ยท Take daily
โญ Newest
๐Ÿ’Š
โœ“ FDA Approved GLP-1 ยท Eli Lilly

Foundayo

Orforglipron ยท Apr 2026

A new GLP-1 pill you can take with or without food. No fasting or timing needed.Approved April 2026, Foundayo works differently from earlier GLP-1 pills. Its unique formulation does not bind to food, meaning you can take it with or without a meal, any time that fits your routine.

Avg. Wt. Loss
12.4%
Form
๐Ÿ’Š Daily Pill
Food Restriction
None
Status
โœ… Approved
Full breakdown โ†’
๐Ÿ’Š
โœ“ FDA Approved GLP-1 ยท Novo Nordisk

Oral Wegovy

Oral Semaglutide ยท 2023

Same results as the Wegovy shot, in pill form. Must be taken on a completely empty stomach every morning.Novo Nordisk's daily pill delivers clinical results comparable to the Wegovy injection. Dosing is strict: taken with plain water on a completely empty stomach, at least 30 minutes before your first food or drink of the day.

Avg. Wt. Loss
15%
Form
๐Ÿ’Š Daily Pill
Food Restriction
Empty stomach
Status
โœ… Approved
Full breakdown โ†’
๐Ÿ’Š
โœ“ FDA Approved GLP-1 ยท Novo Nordisk

Rybelsus

Oral Semaglutide ยท Lower Dose ยท 2019

A diabetes pill sometimes used off-label for weight loss. Lower dose than Oral Wegovy.An oral semaglutide approved for Type 2 diabetes, also used off-label for weight loss. Lower dose than Oral Wegovy, and not the preferred choice if weight loss is your primary goal.

Avg. Wt. Loss
5-10%
Form
๐Ÿ’Š Daily Pill
Food Restriction
Empty stomach
Approved For
Diabetes / Off-label
Full breakdown โ†’
๐Ÿ’‰ FDA-Approved Injections Self-inject ยท Weekly
๐Ÿ’‰
โœ“ FDA Approved GLP-1 ยท Novo Nordisk

Wegovy

Semaglutide Injection ยท 2021

The original weight loss injection. FDA approved and backed by strong clinical trials.The original blockbuster GLP-1 injection. Approved specifically for weight loss and backed by the largest GLP-1 clinical trial ever run at the time of its approval.

Avg. Wt. Loss
15%
Form
๐Ÿ’‰ Weekly
Approved For
Weight Loss
Status
โœ… Approved
Full breakdown โ†’
๐Ÿ’‰
โœ“ FDA Approved GLP-1/GIP ยท Eli Lilly

Zepbound

Tirzepatide Injection ยท 2023

Lost more weight than other options in trials. Uses a dual-hormone approach for stronger results.In clinical trials, patients on Zepbound lost more weight on average than those on semaglutide-only options. Its dual-hormone approach targets appetite and metabolism through two pathways, which is why it outperforms single-hormone options in trials.

Avg. Wt. Loss
21%
Form
๐Ÿ’‰ Weekly
Approved For
Weight Loss
Status
โœ… Approved
Full breakdown โ†’
๐Ÿ’‰
โœ“ FDA Approved GLP-1 ยท Novo Nordisk

Ozempic

Semaglutide Injection ยท Used for Weight Loss ยท 2017

Approved for diabetes but widely used off-label for weight loss. Same ingredient as Wegovy.FDA-approved for Type 2 diabetes, widely prescribed off-label for weight loss. Same active ingredient as Wegovy but at a lower approved dose.

Avg. Wt. Loss
10-15%
Form
๐Ÿ’‰ Weekly
Active Ingredient
Semaglutide
Approved For
Diabetes / Off-label
Full breakdown โ†’
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